痹祺胶囊治疗类风湿关节炎临床观察

目的研究痹祺胶囊治疗类风湿关节炎（rheumatoid arthritis，RA）的临床疗效及适应证。方法RA患者随机分为两组，各71例，其中每组符合湿热痹阻证者36例，符合气虚血瘀证者35例；治疗组采用痹祺胶囊治疗，对照组采用非甾体抗炎药普成片（主要成分为尼美舒利）治疗，用药8周。结果治疗组71例，总有效率66．2％（47例），仅有1例发生轻度不良反应。其中湿热痹阻证36例，总有效率为41．7％；气虚血瘀证35例，总有效率达91．4％，气虚血瘀证疗效好于湿热痹阻证（P〈0．05）。对照组71例，总有效率60．6％（43例）；其中湿热痹阻证36例，总有效率为63．9％；气虚血瘀证35例，总有效率达57．1％；两证型疗效比较差异无显著性（P〉0．05）。结论痹祺胶囊是治疗RA安全有效的药物，尤其对气虚血瘀证疗效更佳。

Clinical Observation on Treatment of Rheumatoid Arthritis with Biqi Capsule

Objective To study the indication and clinical efficacy of Biqi capsule (BC) in treating patients with rheumatoid arthritis (RA). Methods One hundred and forty-two RA patients were randomly divided into the BC treated group and the control group treated with nimesulide tablet (NT). There were 36 patients with dampness-heat blockage syndrome type and 35 patients with Qi deficiency and blood stasis syndrome type in each group. The treatment course lasted for 8 weeks. Results The total effective rate in the BC group was 66.2% (47 cases), while that in the control group was 60.6% (43 cases). The total effective rate in the patients with Qi deficiency and blood stasis syndrome type in the BC group was 91.4%, superior to that with dampness-heat blockage type (41.7%). Only one patient showed mild adverse reaction in the BC group. Conclusion BC is a kind of safe and effective herble medicine for treatment of RA, especially for those of Qi deficiency and blood stasis syndrome type.