| 纳洛酮对心衰犬的血流动力学影响 |
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| 引用本文： | 周明生 陈庆辉. 纳洛酮对心衰犬的血流动力学影响[J]. 江苏医药, 1992, 18(5): 237-239 |
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| 作者姓名： | 周明生 陈庆辉 |
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| 作者单位： | 南京铁道医学院附属医院(周明生，陈庆辉)，南京铁道医学院附属医院(陈日新) |
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| 摘 要： | 本文报道了在异搏定诱导的心衰犬中纳洛酮对血流动力学的影响。结果表明,纳洛酮能明显增加心衰犬的心排量(CO),心指数(CI),降低左室舒张末期压(LVEDP)及肺毛细楔嵌压(PWP)。提示纳洛硐能有效地改善心衰犬的心功能。
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| 关 键 词： | 纳洛酮 心力衰竭 血液动力学 |
The Hemodynamic Effects of Naloxone on in the Heart Failure Dogs |
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| Zhou Mingsheng et al Affiliated Hospital of Nanjing Railway Medical College. The Hemodynamic Effects of Naloxone on in the Heart Failure Dogs[J]. Jiangsu Medical Journal, 1992, 18(5): 237-239 |
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| Authors: | Zhou Mingsheng et al Affiliated Hospital of Nanjing Railway Medical College |
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| Affiliation: | Zhou Mingsheng et al Affiliated Hospital of Nanjing Railway Medical College |
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| Abstract: | Effect of naloxone on hemodynamics was studied inverapamil-induced canineheart failure.Results showed that naloxone could markedly increase cardiac output(CO)and cardiac index(CI).And it could decrease left ventricular end-diastolic pressure(LVEDP)and pulmonary capillary wedge pressure(PWP)in canine heart failure.Theaction of Naloxone may be correlated with the antagonism of cardiac depression resultelfrom the direct inotropic action of endogenous opiate peptideg(EOP). |
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| Keywords: | Naloxone Heart failure Hemodynamics Endogenous opiate peptides |
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