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Diabetic ketoacidosis secondary to L‐asparaginase in acute lymphoblastic leukaemia
Authors:G Gifford  S Milliken  J Greenfield
Institution:1. Department of Haematology, St Vincent's Public Hospital, , Sydney, New South Wales, Australia;2. Department of Endocrinology, St Vincent's Public Hospital, , Sydney, New South Wales, Australia;3. Diabetes and Obesity Research Program, Garvan Institute of Medical Research, , Sydney, New South Wales, Australia
Abstract:We describe a case of severe hyperglycaemia resulting in diabetic ketoacidosis secondary to L‐asparaginase. There are few reports of this potentially life‐threatening complication, particularly in the English literature. Awareness and recognition of this preventable and manageable problem will improve safe delivery of this anti‐leukaemic drug.
Keywords:leukaemia  L‐asparaginase  hyperglycaemia  diabetes  diabetic ketoacidosis  insulin
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