Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids |
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| Authors: | Aya Kakizaki Taku Fujimura Masato Mizuashi Akiko Watabe Yumi Kambayashi Setsuya Aiba |
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| Affiliation: | Department of Dermatology, Tohoku University Graduate School of Medicine, , Sendai, Japan |
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| Abstract: | We describe a 34‐year‐old Japanese man with syringotropic CD8+ mycosis fungoides (MF) accompanied by hypohidrosis who was treated with vorinostat and retinoids. Interestingly, immunohistochemical staining for dermcidin revealed a decrease of sweat in the eccrine glands, and a sweat test by the iodine starch method proved hypohidrosis in the MF‐affected areas. Six months after treatment with this combination therapy, the patient's advanced MF was under control. |
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| Keywords: | CD8+MF hypohidrosis syringotropism vorinostat |
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