|
|||||
|
|
Pre‐diagnosis cigarette smoking and overall survival in non‐Hodgkin lymphoma |
|
| Authors: | Nicholas J Ollberding Andrew M Evens Briseis Aschebrook‐Kilfoy Donne Bennett D Caces Dennis D Weisenburger Sonali M Smith Brian C‐H Chiu |
| Institution: | 1. Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, , Cincinnati, OH, USA;2. Department of Health Studies, University of Chicago, , Chicago, IL, USA;3. Division of Hematology/Oncology, The University of Massachusetts Medical School and the UMass Memorial Cancer Center, , Worcester, MA, USA;4. Division of Hematology/Oncology, Department of Medicine, University of Chicago, , Chicago, IL, USA;5. Department of Pathology, City of Hope National Medical Center, , Duarte, CA, USA;6. University of Chicago Comprehensive Cancer Center, , Chicago, IL, USA |
| Abstract: | We examined whether smoking prior to non‐Hodgkin lymphoma (NHL) diagnosis was associated with overall survival (OS) and conducted a meta‐analysis to assess the evidence relating pre‐diagnosis cigarette smoking with OS. Among 523 NHL patients, worse OS was suggested for greater pre‐diagnostic smoking habits when compared to never smokers. In the meta‐analysis (n = 5 patient populations), inferior OS was observed for greater number of cigarettes smoked per day, years of cigarette smoking, and pack‐years of cigarette smoking. The inferior survival was more pronounced for follicular than for diffuse large B cell lymphoma. Pre‐diagnosis cigarette smoking may adversely impact the survival of NHL patients. |
| Keywords: | cigarettes smoking non‐Hodgkin lymphoma pooled analysis meta‐analysis |