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Felty's syndrome: Effect of lithium on granulopoiesis |
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| Authors: | Ramesh C. Gupta William A. Robinson John E. Kurnick |
| Affiliation: | Denver, Colorado, USA |
| Abstract: | The effect of lithium carbonate upon granulopoiesis was studied in eight patients with Felty's syndrome. Absolute granulocyte counts increased in all patients receiving 900 mg lithium carbonate daily for six weeks. Increased urinary and serum granulocyte colony-stimulating activity was observed in all patients during lithium therapy. A causal relationship between increases in colony-stimulating activity and increased granulocytes is postulated. |
| Keywords: | Requests for reprints should be addressed to Dr. John E. Kurnick University of Colorado Medical Center 4200 East Ninth Avenue Denver Colorado 80220. |
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