Primary Renal Leiomyosarcoma Presenting with Subcutaneous and Osseous Metastases: Staging and Follow-Up with 18F-FDG PET/CT |
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| Authors: | William Makis Fadi Brimo Stephan Probst |
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| Institution: | 1.Diagnostic Imaging,Cross Cancer Institute,Edmonton,Canada;2.MUHC Glen Site, Pathology,Montreal,Canada;3.Jewish General Hospital, Nuclear Medicine,Montreal,Canada |
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| Abstract: | A 60 year old woman who presented with multiple small subcutaneous nodules in the upper back and arms, was referred for an 18F] fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) after histological evaluation revealed metastatic leiomyosarcoma of unknown origin. The PET/CT showed multiple 18F-FDG-avid subcutaneous nodules, bone lesions, as well as a large left renal mass, which was biopsied to confirm a primary renal leiomyosarcoma arising from the renal parenchyma. A post therapy PET/CT showed overall progression of disease. The use of 18F-FDG PET/CT in the staging and evaluation of response to therapy of a renal leiomyosarcoma has not been previously described in the literature. |
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