| 分子蒸馏技术筛选退热止痛散镇痛活性部位研究 |
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| 引用本文： | 周本杰,冯丽娟.分子蒸馏技术筛选退热止痛散镇痛活性部位研究[J].中国药房,2008,19(30):2326-2327. |
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| 作者姓名： | 周本杰 冯丽娟 |
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| 作者单位： | 南方医科大学珠江医院药学部,广州市,510282 |
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| 摘 要： | 目的:筛选退热止痛散的镇痛活性部位。方法:采用超临界CO2流体萃取技术从退热止痛散中提取镇痛活性部位,采用分子蒸馏技术对其进行分离纯化,以镇痛药效为指标,筛选更纯化的镇痛活性部位。结果:分离得到的镇痛活性部位具有很好的镇痛效果。结论:该工艺为基于该活性部位的新药开发提供理论依据。
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| 关 键 词： | 退热止痛散 分子蒸馏 活性部位 |
Screening of the Active Fractions of Antipyretic Analgesics Powder by Molecular Distillation |
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| ZHOU Ben-jie,FENG Li-juan.Screening of the Active Fractions of Antipyretic Analgesics Powder by Molecular Distillation[J].China Pharmacy,2008,19(30):2326-2327. |
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| Authors: | ZHOU Ben-jie FENG Li-juan |
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| Institution: | (Dept.of Pharmacy,Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China) |
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| Abstract: | OBJECTIVE: To study the active fractions from Antipyretic analgesics powder.METHODS:The active fractions were extracted from Antipyretic analgesics powder by supercritical-CO2 fluid extraction technique,separated and purified by molecular distillation(MD) technique.The active fractions were selected with the analgesic effect as index.RESULTS: The active fractions obtained showed remarkable analgesic effect.CONCLUSION: The result serves as a theoretic basis for the development of the active fractions-based new drugs. |
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| Keywords: | Antipyretic analgesics powder Molecular distillation Active fractions |
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