针刺、艾灸膈俞穴对低白细胞模型大鼠白细胞及骨髓造血功能的调节作用

目的　研究针刺或艾灸膈俞穴对低白模型大鼠提升白细胞和增强骨髓增殖功能的作用。方法　选用Wister大鼠为实验对象,用环磷酰胺(CTX)腹腔注射造成白细胞减少及免疫功能抑制模型,分组处理后,在不同时相进行白细胞计数,并计数骨髓有核细胞数,以评估针刺或艾灸膈俞穴的升白及增强骨髓造血功能的作用。结果　针刺、艾灸膈俞穴及常规西药治疗均可显著提升白细胞、增加骨髓有核细胞计数,且艾灸膈俞穴组疗效优于针刺膈俞穴组及常规西药对照组(P<0. 05)。结论　艾灸膈俞穴可明显提升低白模型大鼠外周血白细胞数和骨髓有核细胞计数。

Regulating Effect of Point Geshu Acupuncture and Moxibustion on Leukocyte and Marrow Hematopoiesis in A Rat Model of Leukopenia

Objective To investigate the efficacy of point Geshu acupuncture or moxibustion for raising leukocyte and promoting marrow proliferation.Methods Wister rats were selected as subjects.A model of leukopenia and immunosuppression was made by intraperitoneal injection of cytoxan(CTX).After they were grouped and treated,leukocyte and marrow karyocyte were counted in different phases to evaluate the efficacy of point Geshu acupuncture or moxibustion for raising leukocyte and promoting marrow hematopoiesis.Results Point Geshu acupuncture and moxibustion,and routine Western medicine therapy could all significantly raise leukocyte and increase marrow karyocyte.The curative effect was better in the point Geshu moxibustion group than in the point Geshu acupuncture group and in the routine Western medicine therapy group (P<0.05).Conclusion Point Geshu moxibustion can markedly raise peripheral blood leukocyte and marrow karyocyte in a rat model of leukopenia.