Modification of mammary carcinogenesis and tissue peroxidation by selenium deficiency and dietary fat |
| |
| Authors: | Clement lp |
| |
| Affiliation: | Department of Breast Surgery and Breast Cancer Research Unit , Roswell Park Memorial Institute , Buffalo, NY |
| |
| Abstract: | This study investigates the interdependence of selenium and unsaturated fat intake as modifiers of 1. the incidence of mammary tumors induced by 7, 12‐dimethylbenz (a) anthracene; and 2. the lability of mammary tissue to lipid peroxidation. Results suggest that there is an association between susceptibility of the mammary gland to carcinogenesis and its lability to peroxidation, and that both parameters are intimately regulated by fat intake in conjunction with the selenium status of the animal. |
| |
| Keywords: | |
|
|
