| THE IMMUNOREGULATORY EFFECT OF TLSF_(JM) ON THE EXPRESSION OF T CELL IL-2R AND PROTEIN TYROSINE PHOSPHORYLATION |
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| 作者姓名： | 夏海滨 金伯泉 许辉 赵宁 刘雪松 黄传书 朱勇 李恩善 |
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| 作者单位： | Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian，Department of Immunology，the Fourth Military Medical University，Xian |
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| 摘 要： | The immunoregulatory effect of TLSFJM on the expression of T cell IL- 2R and protein tyrosine phosphorylation ( PTP ) was investigated by immunohistochemistry technique. The results showed that TLSFJMcan markedly suppress the expression of IL-2R and PTP on PHA or TPA-stimulated human PBMC and murine IL-2 dependent cell line CTLL-2. However, there was no effect of TLSFJMon the production of IL-1, IL-2 and IL-6 that play an important role in the course of T lymphocyte proliferation and differentiation.
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The immunoregulatory effect of TLSFJM on the expression of T cell IL-2R and protein tyrosine phosphorylation |
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| Haibin Xia,Boquan Jin,Hui Xu,Ning Zhao,Xuesong Liu,Chuanshu Huang,Yong Zhu,Enshan Li.THE IMMUNOREGULATORY EFFECT OF TLSF_(JM) ON THE EXPRESSION OF T CELL IL-2R AND PROTEIN TYROSINE PHOSPHORYLATION[J].Chinese Journal of Cancer Research,1991,3(4):7-12. |
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| Authors: | Haibin Xia Boquan Jin Hui Xu Ning Zhao Xuesong Liu Chuanshu Huang Yong Zhu Enshan Li |
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| Institution: | 1. Department of Immunology, the Fourth Military Medical University, Xian
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| Abstract: | The immunoregulatory effect of TLSFJM on the expression of T cell IL- 2R and protein tyrosine phosphorylation ( PTP ) was investigated by immunohistochemistry technique. The results showed that TLSFJMcan markedly suppress the expression of IL-2R and PTP on PHA or TPA-stimulated human PBMC and murine IL-2 dependent cell line CTLL-2. However, there was no effect of TLSFJMon the production of IL-1, IL-2 and IL-6 that play an important role in the course of T lymphocyte proliferation and differentiation. |
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| Keywords: | inhibitory factor T lymphocyte activation protein tyrosine phosphorylation immunoregulation |
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