DWI鉴别诊断实质性肝脏肿瘤的价值

目的 探讨DWI鉴别诊断实质性肝脏良性与恶性肿瘤的价值。 方法 回顾性分析经病理证实的7例肝腺瘤、14例肝局灶性增生(FNH)及32例肝脏恶性肿瘤患者(25例肝癌和7例转移瘤)的DWI定量分析结果,比较肝脏FNH和腺瘤与肝脏恶性肿瘤ADC值的差异。 结果 7例肝腺瘤9个病灶的平均ADC值为(1.05±0.28)×10^-3 mm²/s,14例FNH 18个病灶的平均ADC值为(1.13±0.46)×10^-3 mm²/s,32例肝脏恶性肿瘤49个病灶的平均ADC值为(0.96±0.29)×10^-3 mm²/s(b＝800 s/mm²)。FNH、肝腺瘤与肝脏恶性肿瘤的平均ADC值之间差异无统计学意义(P均>0.05)。 结论 ADC值对实质性肝脏良性肿瘤(FNH和肝腺瘤)与肝脏恶性肿瘤的鉴别无帮助。

Value of DWI in differential diagnosis of solid liver neoplasms

Objective To observe the differential diagnostic value of DWI for benign and malignant hepatic tumors. Methods ADC values were measured in 53 patients with solid hepatic tumor (7 adenomas, 14 focal nodular hyperplasia , 25 hepatocellular carcinoma and 7 metastases) confirmed by pathology. The difference of ADC value of malignant tumors with FNH and adenomas were compared. Results The mean ADC values for adenomas (9 lesions), FNH (18 lesions), and malignant tumors (49 lesions) was (1.05±0.28)×10^-3 mm²/s, (1.13±0.46)×10^-3 mm²/s, and (0.96±0.29)×10^-3 mm²/s, respectively. There was no significant difference in ADC values between solid benign hepatic tumors and malignant neoplasms. Conclusion ADC values can not help to differentiate benign and malignant solid liver neoplasms.