TIA患者脑动脉微栓子的监测及其与颈动脉斑块的相关性

目的 监测短暂性脑缺血发作(TIA)患者脑动脉微栓子(MES)的出现率,探讨其与颈动脉斑块的相关性.方法 112例TIA患者均进行MES的监测和颈动脉彩色多普勒超声检测,分别观察MES阳性与有颈动脉斑块的病例数.结果 (1)MES阳性者31例,阳性率27.68%.有颈动脉斑块者67例,斑块出现率59.82%,其中不稳定斑块28例,占有斑块病例的41.79%.(2)67例有斑块者MES阳性率35.82%,较45例无斑块者15.56%高(P<0.05);28例不稳定斑块者MES阳性率57.14%,较39例稳定斑块者20.51%高(P<0.01).(3)MES与斑块的大小、部位和个数无相关性.结论 颈动脉不稳定斑块的脱落是TIA患者脑动脉MES的主要来源之一,稳定颈动脉斑块的处理是减少TIA复发及其后出现脑梗死的重要举措.

Abstract：

Objective To study the prevalence of cerebral microembolism(MES)in patients with TIA and its relation to carotid plaque.Methods Total 112 patients with TIA were studied.The cerebral artery MES were monitored by TCD.and carotid plaques were detected by color transcranial Doppler.The cases with cerebral artery MES and with carotid plaques were respectively recorded.Results There were 31 patients with MES and the prevalence WaS 27.68%.There were 67 patients with carotid plaques and the presence was 59.82%;among them,28 patients with unstable carotid plaques constituted 41.79%.The prevalence of MES in 67 patients with carotid plaques(35.82%)Was significantly hisher than 45 patients without carotid plaques(15.56%)(P<0.05),while the prevalence of MES in 28 patients with unstable carotid plaques(57.14%)was greatly higher than 39 patients with stable carotid plaques(20.51%)(P<0.01).The prevalence of MES had nothing to do with the size,position and quantity of the carotid plaque.Conclusions The desquamation of unstable carotid plaque is one of the main sources of cerebral artery MES.The stabilization of carotid plaque is an important measure to reduce relapse of TIA and prevent the patient from cerebral infarction after TIA.

Cerebral microembolism monitoring in patients with transient ischemic attack and its relation to carotid plaque

Objective To study the prevalence of cerebral microembolism(MES)in patients with TIA and its relation to carotid plaque.Methods Total 112 patients with TIA were studied.The cerebral artery MES were monitored by TCD.and carotid plaques were detected by color transcranial Doppler.The cases with cerebral artery MES and with carotid plaques were respectively recorded.Results There were 31 patients with MES and the prevalence WaS 27.68%.There were 67 patients with carotid plaques and the presence was 59.82%;among them,28 patients with unstable carotid plaques constituted 41.79%.The prevalence of MES in 67 patients with carotid plaques(35.82%)Was significantly hisher than 45 patients without carotid plaques(15.56%)(P<0.05),while the prevalence of MES in 28 patients with unstable carotid plaques(57.14%)was greatly higher than 39 patients with stable carotid plaques(20.51%)(P<0.01).The prevalence of MES had nothing to do with the size,position and quantity of the carotid plaque.Conclusions The desquamation of unstable carotid plaque is one of the main sources of cerebral artery MES.The stabilization of carotid plaque is an important measure to reduce relapse of TIA and prevent the patient from cerebral infarction after TIA.