| 痰瘀同治方对鸡胚绒毛尿囊膜血管新生的影响 |
| |
| 引用本文： | 朱盛,刘建勋.痰瘀同治方对鸡胚绒毛尿囊膜血管新生的影响[J].中华中医药杂志,2012(5):1292-1294. |
| |
| 作者姓名： | 朱盛 刘建勋 |
| |
| 作者单位： | 中国中医科学院西苑医院 |
| |
| 基金项目： | 重大新药创制(No.2009ZX09303-003,No.2009ZX09301-005-2-6)~~ |
| |
| 摘 要： | 目的:探讨痰瘀同治方对鸡胚绒毛尿囊膜血管新生的影响。方法:将8日龄鸡胚制备鸡胚绒毛尿囊膜(CAM)模型随机分为4组:空白血清组,大、中、小剂量含药血清组(加入各组相应的含药血清)。培养3d后观察各组对CAM模型标本形态及血管新生数量的影响。结果:大剂量含药血清组粗大血管及细小分支迅速增多,血管网络清晰,呈叶脉样,放射性生长,血管新生数量明显高于空白血清组(P<0.01),中剂量及小剂量含药血清组与空白血清组比较有一定优势,但无统计学意义。结论:痰瘀同治方可明显促进鸡胚绒毛尿囊膜血管新生。
|
| 关 键 词： | 含药血清 血管新生 鸡胚绒毛尿囊膜模型 |
Effect of formula of Tan Yu Tong Zhi on angiogenesis in chicken embryo allantois membrane |
| |
| ZHU Sheng,LIU Jian-xun.Effect of formula of Tan Yu Tong Zhi on angiogenesis in chicken embryo allantois membrane[J].China Journal of Traditional Chinese Medicine and Pharmacy,2012(5):1292-1294. |
| |
| Authors: | ZHU Sheng LIU Jian-xun |
| |
| Institution: | (Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China) |
| |
| Abstract: | Objective: To observe the effect of formula of Tan Yu Tong Zhi for promoting angiogenesis on chofio-auantoic membrance(CAM).Methods: Prepare model of CAM,use medicated serum of the formula of Tan Yu Tong Zhi on CAM,The breeding eggs were divided into 4 groups: high-dose,medium-dose,low-dose and blank control serum.Growth shape of chicken embryo and vessels count of CAM model in each group were observed after 3 days.Results: The vasculature growth was rapidly in the medication group with high-dose.The primary and secondary vessels were promoted in the groups with high-dose,which was significantly different from normal serum group(P<0.01).There was no significant difference between the medium-dose and normal serum group.Conclusion: The fomula of Tan Yu Tong Zhi showed obvious promotion effects on CAM angiogenesis. |
| |
| Keywords: | Medicated serum Angiogenesis CAM |
| 本文献已被 CNKI 等数据库收录！ |
|
