核素肝脾显像评估部分性脾栓塞术疗效

目的探讨核素肝脾显像在评估部分性脾栓塞术（ＰＳＥ）疗效中的价值。方法对２０例肝硬化脾功能亢进病人ＰＳＥ治疗前后进行放射性核素肝脾显像。应用感兴趣区技术测定肝、脾区活性，计算脾栓塞分数（ＦＳＥ），并对ＦＳＥ与疗效及并发症间的关系进行相关分析。结果随着ＦＳＥ的增高，术后发热时间延长；术后白细胞和血小板等明显恢复，且与ＦＳＥ有明显的相关关系，ｒ分别为０６３８（Ｐ＜００５）和０８５６（Ｐ＜００１）。５例术后出现并发症的病人ＦＳＥ均在７０％以上。结论核素肝脾显像定量测定ＦＳＥ简便易行，可为临床医师准确掌握部分性脾栓塞体积和评估疗效等提供较可靠的客观依据；ＦＳＥ控制在４０％～７０％时ＰＳＥ治疗可取得较满意的疗效。

Application of liver spleen radionuclide scintigraphy in partial spleen embolization

Purpose To investigate the value of liver spleen radionuclide scintigraphy in therapeutic of partial spleen embolization (PSE) Methods Liver spleen radionuclide scintigraphy was performed in 20 patients with cirrhosis and hypersplenism before and after therapeutic partial spleen embolization The fraction of spleen embolization (FSE) and spleen activity index (SAI) were calculated using region of interest (ROI) technique The correlation analyses were made between FSE and efficacy of PSE and its complications Results The results showed that the larger the FSE was, the longer the postoperative fever lasted The recovery of white blood cell and platelet counts were significant after PSE and highly correlated with FSE (r=0 638, P<0 05, and r=0 856, P<0 01) Complications occured in 5 patients with FSE above 70% Conclusions Quantitative measurement of FSE by liver spleen radionuclide/scintigraphy is simple and easy, provides objective and reliable data of the embolized spleen fraction and the therapeutic effectiveness for clinicians The results indicate that better therapeutic results come along with FSEs ranged from 40% to 70%