| 华东和华南地区商品猪戊型肝炎病毒携带率和基因分型分析 |
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| 引用本文： | 夏玉刚,陆一涵,胡安群,秦雪,董晓莲,朱建福,姜庆五,郑英杰.华东和华南地区商品猪戊型肝炎病毒携带率和基因分型分析[J].中华流行病学杂志,2009,31(11):791-794. |
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| 作者姓名： | 夏玉刚 陆一涵 胡安群 秦雪 董晓莲 朱建福 姜庆五 郑英杰 |
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| 作者单位： | 复旦大学公共卫生学院流行病学教研室教育部公共卫生安全重点实验室,上海,200032;安徽省安庆市立医院;广西医科大学第一附属医院;浙江省德清县疾病预防控制中心; |
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| 基金项目： | 国家自然科学基金上海市重点学科建设项目 |
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| 摘 要： | Objective To determine the prevalence and genotype of hepatitis E virus (HEV)among commercial swine population in Eastern and Southern China. Methods Six hundred specimens of swine bile collected from 5 slaughterhouses in Eastern and Southern China from 2007 to 2009 were tested for HEV RNA using nested RT-PCR. PCR products were sequenced for phylogenetic analysis. Results Forty-seven out of the 600 samples (7.83%) were positive for HEV RNA. Based on the 150 nt fragment within HEV ORF2, data from phylogenetic analysis revealed that all the 47 HEV isolates were identified to be genotype Ⅳ, sharing 75.0%-83.4%, 75.0%-84.6%, 71.9%-80.7% and 88.1%-91.5% nucleotide identities with prototype Ⅰ,Ⅱ,Ⅲ and Ⅳ HEV strains respectively while majority of the isolates clustered within their respective isolation sites. Conclusion HEV was widespread in commercial swine population in Eastern and Southern China that raised a serious concern about the safety regarding the consumption of pork products.
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| 关 键 词： | 戊型肝炎病毒 携带率 基因型 猪 |
Study on the prevalence and genotype of hepatitis E virus among commercial swine population in Eastern and Southern China |
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| XIA Yu-gang,LU Yi-han,HU An-qun,QIN Xue,DONG Xiao-lian,ZHU Jian-fu,JIANG Qing-wu,ZHENG Ying-jie.Study on the prevalence and genotype of hepatitis E virus among commercial swine population in Eastern and Southern China[J].Chinese Journal of Epidemiology,2009,31(11):791-794. |
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| Authors: | XIA Yu-gang LU Yi-han HU An-qun QIN Xue DONG Xiao-lian ZHU Jian-fu JIANG Qing-wu ZHENG Ying-jie |
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| Abstract: | |
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| Keywords: | Hepatitis E virusPrevalenceGenotypeSwine |
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