可疑冠心病患者核素显像与CT冠状动脉造影对比分析

Objective The aim of this study was to analyze the relationship between myocardial perfusion imaging (MPI) and computed tomography coronary artefiography (CTCA) in diagnosis of patients with suspected coronary artery disease (CAD).Methods Forty patients with suspected CAD underwent invagive coronary angiography(CAG),MPI and CTCA within 2 months.The results of myocardial perfusion imaging were classified as normal or abnormal[reversible and(or)fixed defects] ;The CTCA studies were classified as normal,non-obstructive(＜50% stenosis)CAD,or obstructive CAD.Taking the results of CAG as"gold standard",the findings of MPI and CTCA were comparatively analyzed.Concordant and discordant results between MPI and CTCA were statistically analyzed using Kappa test.P＜0.05 Was considered statistically significant.Results Aboat 90.1% patients with normal CTCA also showed normal MPI.However,only 44.8% patients with abnormal CTCA showed corresponding perfusion abnormalities on MPI.Conversely,61.5% patients with normal MPI had abnormal CTCA.Compared with CAG,the sensitivity,specificity and accuracy of CTCA were 96.4%(27/28),83.3%(10/12) and 92.5%(37/40),and those of MPI were 46.4%(13/28),91.7%(11/12)and 60.0%(24/40) respectively.Conclusions MPI and CTCA provide different but complementary information in diagnosis of patients with suspected CAD.Their clinical value and application should be practically combined.

Comparative analysis of myocardial perfusion imaging and CT coronary arteriography in diagnosis of patients with suspected coronaryartery disease