| 幽门螺杆菌与反流性食管炎发病关系的探讨 |
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| 引用本文： | 王少鑫,刘超群,浦江,付山峰,岳鑫. 幽门螺杆菌与反流性食管炎发病关系的探讨[J]. 中国医药, 2009, 4(8): 868-869. DOI: 10.3760/cma.j.issn.1673-4777.2009.11.017 |
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| 作者姓名： | 王少鑫 刘超群 浦江 付山峰 岳鑫 |
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| 作者单位： | 海军总医院消化科,北京,100037; |
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| 摘 要： | 目的 探讨幽门螺杆菌(Hp)与反流性食管炎(RE)发病的关系.方法 回顾性分析2004年1月至2008年5月行胃镜检查患者的报告,将内镜下RE阳性286例患者作为研究组进行分级,选择同期行内镜检查的非RE慢性胃炎250例患者为对照组,统计2组Hp阳性率并进行比较.结果 研究组Hp感染率为28.7%(82/286),明显低于对照组的48.4%(121/250)(χ2=21.01,P=0.00).研究组中无论是否存在Hp感染均以轻度食管炎多见,而且其Hp感染率32.0%要高于重度食管炎17.2%,组间比较差异有统计学意义(χ2=5.153,P<0.05).结论 Hp在食管炎的发病过程中与消化性溃疡等疾病不同,并非主要致病因素.
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| 关 键 词： | 反流性食管炎 幽门螺杆菌 病因学 |
Relation between H. pylori and reflux esophagitis'pathogeny |
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| Abstract: | Objective To observe the relation between H. pylori and reflux esophagitis' pathogeny. Methods Gastroscopy reports on reflux esophagitis in the last four years were reviewed, reflux esophagitis was gra-ded and HP positive rate in different groups was calculated. Results The Hp positive rate(28.7%) in RE group was lower than that in control group. Low-grade esophagitis was primary in patients infected by Hp or not, with a higher Hp positive rate(32.0%)than high-grade esophagitis group(17.2%)(P<0.05) Conclusion Hp is not the main pathogeny of reflux esophagitis, which is different from peptic ulcer disease. |
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| Keywords: | Reflux esophagitisH. pyloriPathogeny |
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