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肝癌CT影像人工神经网络辅助诊断模型的评价
引用本文:张波,张治英,徐德忠,闫永平,彭勇,夏结来,秦明新,宋振顺,高凯,姜建辉,贾娟,李琼. 肝癌CT影像人工神经网络辅助诊断模型的评价[J]. 西南国防医药, 2005, 15(5): 475-479
作者姓名:张波  张治英  徐德忠  闫永平  彭勇  夏结来  秦明新  宋振顺  高凯  姜建辉  贾娟  李琼
作者单位:1. 第四军医大学预防医学系流行病教研室,陕西,西安,710032
2. 第四军医大学预防医学系统计教研室,陕西,西安,710032
3. 第四军医大学生物医学医电工程教研室,陕西,西安,710032
4. 第四军医大学西京医院肝胆外科,陕西,西安,710032
5. 第四军医大学西京医院放射科,陕西,西安,710032
6. 西安陆军学院门诊部,陕西,西安,710000
摘    要:目的:评价人工神经网络辅助诊断模型应用于肝癌CT影像诊断的真实性和可靠性.方法:以临床各期肝癌和其它肝占位疾病的CT影像特征数据为训练样本集,建立肝癌CT影像人工神经网络辅助诊断模型,并确定该神经网络应用于肝癌CT影像诊断的截断点;同时,将另外收集的肝癌和其它肝占位疾病CT影像特征数据通过神经网络进行仿真运算,得到网络诊断输出,计算该神经网络模型应用于肝癌CT影像诊断的真实性和可靠性.结果:神经网络用于肝癌CT影像诊断的灵敏度和特异度分别为:98.0%和96.0%,诊断准确度为97.0%;进一步计算该神经网络模型诊断可靠性,其诊断符合率为91.0%,卡帕值为0.82(Z=4.8,P<0.05).结论:人工神经网络模型可以应用于肝癌CT影像的临床诊断.

关 键 词:人工神经网络 肝细胞癌 计算机断层扫描 诊断试验
文章编号:1004-0188(2005)05-0475-05
收稿时间:2005-06-10
修稿时间:2005-06-10

Evaluation of assistant diagnosis model based on artificial neural network in hepatocellular carcinoma CT imaging
ZHANG Bo,ZHANG Zhi-ying,XU De-zhong,YANG Yong-ping,PENG Yong,XIA Jie-lai,QIN Ming-xin,SONG Zhen-shun,GAO Kai,JIANG Jian-hui,JIA Juan,LI Qiong. Evaluation of assistant diagnosis model based on artificial neural network in hepatocellular carcinoma CT imaging[J]. Medical Journal of National Defending forces in Southwest China, 2005, 15(5): 475-479
Authors:ZHANG Bo  ZHANG Zhi-ying  XU De-zhong  YANG Yong-ping  PENG Yong  XIA Jie-lai  QIN Ming-xin  SONG Zhen-shun  GAO Kai  JIANG Jian-hui  JIA Juan  LI Qiong
Abstract:Objective: To evaluate the validity and reliability of assistant diagnosis model based on artificial neural network(ANN) in hepatocellular carcinoma(HCC) CT imaging.Methods: The CT imaging of HCC(n=100) and other liver occupational diseases(n=100) were collected and their features were identified for the training database.The ANN for diagnosis of HCC CT imaging was constructed with a back-propagation training algorithm. Based on the emulational operation by ANN,a network diagnosis was made.The validity and reliability of ANN for HCC diagnosis were calculated.Results: The sensitivity,specificity and accuracy of ANN for diagnosis of HCC CT imaging were 98%,96% and 97%,respectively,the diagnostic consilient rate was 91% and ksppa value was 0.82(Z=4.8.P<0.01).Conclusion: It is suggested that the ANN may be used for clinical diagnosis of HCC.Abstract:Objective:To evaluate the validity and reliability of assistant diagnosis model based on artificial neural network(ANN) in hepatocellular carcinoma(HCC) CT imaging.Methods:The CT imaging of HCC(n=100) and other liver occupational diseases(n=100) were collected and their features were identified for the training database.The ANN for diagnosis of HCC CT imaging was constructed with a back-propagation training algorithm.Based on the emulational operation by ANN,a network diagnosis was made.The validity and reliability of ANN for HCC diagnosis were calculated.Results:The sensitivity,specificity and accuracy of ANN for diagnosis of HCC CT imaging were 98%,96% and 97%,respectively,the diagnostic consilient rate was 91% and ksppa value was 0.82(Z=4.8.P <0.01).Conclusion:It is suggested that the ANN may be used for clinical diagnosis of HCC.
Keywords:artificial neural network   assistant diagnosis   hepatocellular carcinoma   diagnosis
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