ATP-sparing effect of histochrome in acute myocardial ischemia in patients with coronary heart disease |
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| Authors: | S. A. Afanas'ev T. V. Lasukova A. M. Chernyavskii |
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| Affiliation: | (1) Institute of Cardiology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |
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| Abstract: | Afterin vitro ischemia, the content of adenosine triphosphate in myocardial bioptates from patients with heart diseases is reduced. This reduction is more pronounced in patients with coronary heart disease than in patients with rhythm disturbances. Administration of the antioxidant preparation histochrome to patients with coronary heart disease preserves ATP during ischemic exposure. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 12, pp. 669–671, December, 1997 |
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| Keywords: | myocardium ischemia ATP lipid peroxidation antioxidants |
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