| EPO-R 和CD31 在前列腺癌中的表达及其意义 |
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| 引用本文： | 张晓毅,洪宝发,陈光富,吕亚莉,钟梅. EPO-R 和CD31 在前列腺癌中的表达及其意义[J]. 肿瘤防治研究, 2005, 32(7): 409-410,456 |
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| 作者姓名： | 张晓毅 洪宝发 陈光富 吕亚莉 钟梅 |
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| 作者单位： | 1. 100853,北京,中国人民解放军总医院泌尿外科
2. 100853,北京,中国人民解放军总医院病理科 |
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| 摘 要： | 目的 探讨EPO-R和CD31在前列腺癌中表达及其临床意义。方法 采用免疫组化的方法对51例前列腺癌手术标本及10例前列腺增生手术标本进行标记及分析。结果 显示EPO-R和CD31表达与前列腺癌的病理分级、Gleason评分及转移密切相关，并具有显著性差异，但与血清前列腺特异性抗原(PSA)水平无关。结论 EPO-R和CD31的表达可能在前列腺癌的发展及转移过程中起重要作用。
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| 关 键 词： | EPO-R CD31 前列腺癌 |
| 文章编号： | 1000-8578(2005)07-0409-02 |
| 收稿时间： | 2004-12-06 |
| 修稿时间： | 2005-03-09 |
Significance of CD31 and EPO-R Expression in Prostate Cancer |
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| ZHANG Xiao-yi,HONG Bao-Fa,CHEN Guang-fu,LV Ya-li,ZHAONG Mei. Significance of CD31 and EPO-R Expression in Prostate Cancer[J]. Cancer Research on Prevention and Treatment, 2005, 32(7): 409-410,456 |
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| Authors: | ZHANG Xiao-yi HONG Bao-Fa CHEN Guang-fu LV Ya-li ZHAONG Mei |
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| Affiliation: | 1. Department of Urology , China PLA General Hospital , Beijing 100853 , China; 2. Department of Pathology |
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| Abstract: | Objective To evaluate the role of erythropoietin receptor ( EPO-R) and CD31 in the Prostate cancer ( Pca) . Methods Fif ty 3/one cases of Pca and ten cases of benign prostate hyperplasia (BpH) were studied by immunohistochmcal method using monocolonal antibody to EPO-R and CD31. Results It was showed that there were significantly correlation between EPO-R or CD31 and Grade , Score of Gleason and metastasis of Pca. Conclusion The expression of EPO-R and CD31 may play a important role in the development and metastasis of Pca. |
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| Keywords: | EPO-R CD31 Prostate cancer |
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