| 血浆一氧化氮在小儿充血性心力衰竭时的变化及意义 |
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| 引用本文： | 吕兴,蔡定邦,梁星群,陈享,刘凌.血浆一氧化氮在小儿充血性心力衰竭时的变化及意义[J].中国基层医药,2003,10(2):126-127. |
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| 作者姓名： | 吕兴 蔡定邦 梁星群 陈享 刘凌 |
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| 作者单位： | 526021,广东肇庆市第一人民医院儿科 |
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| 摘 要： | 目的 探讨小儿充血性心力衰竭(CHF)时血浆一氧化氮(NO)的变化及意义。方法 测定先天性心脏病合并CHF组17例与健康小儿作对照组15例、支气管肺炎(支肺炎)合并CHF组16例与支气管肺炎组15例及支肺炎合并CHF纠正前后的血浆NO水平。结果 先天性心脏病合并CHF组的血浆水平高于对照组且差异有非常显著意义(P＜0．001)，支肺炎合并CHF组(CHF纠正前)的血浆NO水平高于支肺炎组且差异有非常显著意义(P＜0．001)。结论 CHF患儿的血浆NO水平升高是CHF患儿的病理生理特征之一，N0参与CHF的病理生理，可作为判断CHF的一个辅助指标。
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| 关 键 词： | 血浆 一氧化氮 小儿 充血性心力衰竭 |
| 修稿时间： | 2002年5月28日 |
The changes and its significance of plasma nitric oxide in children with congestive heart failure |
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| LU Xing,CAI Dingbang,LIANG Xingqun,et al..The changes and its significance of plasma nitric oxide in children with congestive heart failure[J].Chinese Journal of Primary Medicine and Pharmacy,2003,10(2):126-127. |
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| Authors: | LU Xing CAI Dingbang LIANG Xingqun |
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| Institution: | LU Xing,CAI Dingbang,LIANG Xingqun,et al.Department of Peditrics,The First People's Hospital of Zhaoqing,Guangdong,526021 |
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| Abstract: | Objective To study the effect of plasma nitric oxide(NO) levels on children with congestive heart failure(CHF).Methods The plasma NO was measured in 16 children with CHF due to congenital heart desease(CHD) and 15 healthy children as control group,16 children with CHF due to bronchopneumonia and 15 children with bronchopneumoina.Results The plasma NO of children with CHF due to CHD and bronchopneumonia increased remarkably comparied with the control group and children with bronchopneumonia(P<0.001).Conclusion NO plays important role in the pathophysio logic change of CHF.The plasma NO can be used as a parameter of CHF. |
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| Keywords: | Nitric oxide(NO) Children congestive heart failure |
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