| 冷应激大鼠血浆及回肠P物质和VIP的变化 |
| |
| 引用本文： | 李利生,曲瑞瑶,郭华,王伟,孟阳.冷应激大鼠血浆及回肠P物质和VIP的变化[J].首都医学院学报,2002,23(2):113-114. |
| |
| 作者姓名： | 李利生 曲瑞瑶 郭华 王伟 孟阳 |
| |
| 作者单位： | 首都医科大学生理学教研室
(李利生，曲瑞瑶，郭华，王伟)，首都医科大学生理学教研室(孟阳) |
| |
| 摘 要： | 采用放免法对冷束缚应激大鼠血浆及回肠始段P物质 (SP)、血管活性肠肽 (VIP)进行测定。发现与正常对照组相比 ,应激组回肠段SP含量无明显改变 ,VIP含量降低 (P <0 .0 5 ) ;应激组血浆中SP质量浓度明显增加 (P <0 .0 1 ) ,VIP质量浓度则明显降低 (P <0 .0 1 )。提示 :应激组大鼠回肠始段及血浆SP、VIP的改变 ,可能与其胃肠功能变化的调节有关。
|
| 关 键 词： | 应激 P物质(SP) 血管活性肠肽(VIP) |
| 收稿时间： | 2001-12-11 |
| 修稿时间： | 2001年12月11 |
Changes of SP and VIP in Blood and Ileum of Cool Stress Rats |
| |
| Li Lisheng,Qu Ruiyao,Guo Hua,Wang Wei,Meng Yang.Changes of SP and VIP in Blood and Ileum of Cool Stress Rats[J].Journal of Capital University of Medical Sciences,2002,23(2):113-114. |
| |
| Authors: | Li Lisheng Qu Ruiyao Guo Hua Wang Wei Meng Yang |
| |
| Institution: | Li Lisheng,Qu Ruiyao,Guo Hua,Wang Wei,Meng Yang Department of Physiology,Capital University of Medical Sciences |
| |
| Abstract: | Substance P (SP) and vasoactive intestinal peptide (VIP) levels in blood and all layers of initial part of ileum in rats were measured by radioimmunoassays (RIA) in order to explore the mechanism of cool stress. SP levels in ileum of cool stress didn't change while the VIP levels in ileum of cool stress were significantly lower than the controls groups(P<0.05). SP levels in blood of cool stress were significantly higher (P<0.01) while the VIP levels in blood of cool stress were significantly lower than the controls groups(P<0.01). The results shows that changes of SP and VIP levels in the initial part ileum and blood of cool stress may be related to the gastrointestinal motility disorders presented in cool stress rats. |
| |
| Keywords: | stress substance P (SP) vasoactive intestinal peptide (VIP) |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《首都医学院学报》浏览原始摘要信息 |
| 点击此处可从《首都医学院学报》下载免费的PDF全文 |
|
