NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis |
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| Authors: | Dela Peña Aileen Leclercq Isabelle Field Jacqueline George Jacob Jones Brett Farrell Geoffrey |
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| Affiliation: | Storr Liver Unit, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Sydney, NSW, Australia. |
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| Abstract: | |
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| Keywords: | Ad5mIκB, adenovirus-expressing mIκB superrepressor Ad5LacZ, adenovirus-expressing LacZ ASH, alcoholic steatohepatitis CTL, control GAPDH, glyceraldehyde-3-phosphate dehydrogenase HA, hemagglutinin ICAM-1, intercellular adhesion molecule-1 IκB, inhibitor of NF-κB MCD, methionine and choline deficient NAFLD, nonalcoholic fatty liver disease NASH, nonalcoholic steatohepatitis NF-κB, nuclear factor-κB NPC, nonparenchymal cell TBARS, thiobarbituric acid-reactive substance TNF, tumor necrosis factor TNFR-1, tumor necrosis factor receptor-1 wt, wild-type |
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