| 血液灌流对急性重度有机磷中毒的疗效评价 |
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| 引用本文： | 何飞,邱俏檬,卢中秋,粱欢,刘刚,李蕊.血液灌流对急性重度有机磷中毒的疗效评价[J].中国急救医学,2008,28(11):974-977. |
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| 作者姓名： | 何飞 邱俏檬 卢中秋 粱欢 刘刚 李蕊 |
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| 作者单位： | 温州医学院附属第一医院急诊科,浙江,325000 |
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| 基金项目： | 浙江省医学扶植重点建设学科计划项目 |
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| 摘 要： | 目的 评价血液灌流治疗急性重度有机磷中毒的疗效.方法 选取1999-2007年间收住我院经洗胃、阿托品、氯磷定、抗感染及呼吸支持等综合治疗且临床资料完整的急性重度有机磷中毒患者71例,其中经血液灌流治疗35例,未经血液灌流治疗36例,对照分析两组患者临床效果.结果 血液灌流组患者灌流后血CHE水平显著回升(P<0.01),血WBC、PLT和Cr明显下降(P<0.01或P<0.05),血PT明显延长(P<0.05).与非血液灌流组比较,血液灌流组患者入院24 h后血CHE水平明显回升(P<0.05),阿托品总用量、呼吸机使用时间、住院时间均明显下降(P<0.05),并发症(中间期肌无力综合征、肺部感染、呼吸衰竭等)明显减少(P<0.01或P<0.05),治愈率明显提高(P<0.05),而住院费用无明显变化(P>0.05).结论 对急性重度有机磷中毒患者在综合治疗基础上加用血液灌流,治疗效果显著,值得在急诊科进一步推广应用.
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| 关 键 词： | 重度有机磷中毒 血液灌流 治疗效果 |
To evaluate the curative effect of hemoperfusion in the treatment of acute severe organophosphate poisoning |
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| HE Fei,QIU Qiao-meng,LU Zhong-qiu,et al..To evaluate the curative effect of hemoperfusion in the treatment of acute severe organophosphate poisoning[J].Chinese Journal of Critical Care Medicine,2008,28(11):974-977. |
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| Authors: | HE Fei QIU Qiao-meng LU Zhong-qiu |
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| Institution: | HE Fei,QIU Qiao-meng,LU Zhong-qiu,et al.Emergency Department,the First Affiliated Hospital of Wenzhou Medical College,Wenzhou 325000,China |
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| Abstract: | Objective To evaluate the curative effect of hemoperfusion in the treatment of acute organophosphate poisoning(AOPP).Methods 71 cases with AOPP in our hospital from 1999 to 2007 were divided into hemoperfusion group(n=35) and non-hemoperfusion group(n=36).Both of them were given combined treatment (gastric lavage,atropine,pralidoxime chloride,anti-infection,respiratory support and so on).The differences of the clinical curative effect between two groups were analysed.Result In hemoperfusion group,serum chol... |
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| Keywords: | Severe organophosphate poisoning Hemoperfusion Curative effect |
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