| 慢性阻塞性肺疾病患者血液流变学指标及ET、SOD水平变化的临床观察 |
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| 引用本文： | 陈章,白小红,王利,关静.慢性阻塞性肺疾病患者血液流变学指标及ET、SOD水平变化的临床观察[J].微循环学杂志,2011,21(2):30-31,7,11. |
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| 作者姓名： | 陈章 白小红 王利 关静 |
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| 作者单位： | 1. 成都军区总医院呼吸内科,成都,610083
2. 四川乐山市人民医院 |
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| 摘 要： | 目的:观察慢性阻塞性肺疾病(COPD)患者血液流变学指标及血浆内皮素(ET)和血清超氧化物歧化酶(SOD)水平的变化。方法:采用自动血流变测试仪测定COPD患者血液流变学指标,用RIA法测定血浆ET和血清SOD水平,并与健康对照组比较。结果:COPD患者血液流变学指标有明显变化,低切变率和高切变率全血粘度以及血浆粘度均增高,与对照组比较差异显著(P<0.05),血浆ET浓度明显高于对照组(P<0.01),而血清SOD含量明显低于对照组(P<0.05)。结论:COPD患者血液流变学指标异常、微循环障碍以及ET和SOD血液水平的变化是其病理改变的重要环节。
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| 关 键 词： | 慢性阻塞性肺疾病 血液流变学 内皮素 超氧化物歧化酶 |
Clinical Study on Changes of Hemorheology, Endothelin and Superoxide Dismutase in Patients with Chromic Obstructive Pulmonary Disease |
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| Chen Zhang,Bai Xiaohong,Wang Li,et al/.Clinical Study on Changes of Hemorheology, Endothelin and Superoxide Dismutase in Patients with Chromic Obstructive Pulmonary Disease[J].Chinese Journal of Microcirculation,2011,21(2):30-31,7,11. |
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| Authors: | Chen Zhang Bai Xiaohong Wang Li / |
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| Institution: | Chen Zhang,Bai Xiaohong,Wang Li,et al/Department of Respiratory Medicine,Chengdu Army General Hospital,Chengdu,610083 |
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| Abstract: | Objective:To study the changes of hemorheology,endothelin(ET) and superoxide dismutase(SOD)in patients with chronic obstructive pulmonary disease(COPD).Method:Hemorheoloical index in 62 patients with COPD and 60 person in control group were examined by SA-6000 type auto-hemorheological examin instrument.Serum ET and SOD was measured by RIA.Results:Differential change of hemorheology index in the patients with COPD had occurred.Blood viscosity and serum viscosity were increased.Hemorheoloical index of COPD g... |
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| Keywords: | Chronic obstructive pulmonary disease Hemorheology ET SOD |
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