微创血肿清除术后高压氧联合依达拉奉治疗高血压脑出血疗效观察

目的观察微创血肿清除术后早期高压氧联合依达拉奉治疗高血压脑出血的临床疗效。方法高血压脑出血微创血肿清创术后患者216例,随机分为联合治疗组（高压氧＋依达拉奉）76例、单纯高压氧组66例及依达拉奉组74例。采用Scandinavian中风量表（Scandinavian Stroke Scale,SSS）及改良Rankin量表（modified Rankin scale,mRS）评分法评估三组的临床疗效。结果治疗14 d后,与高压氧组比较,联合治疗组和依达拉奉组SSS评分均显著增高（P=0.005〈0.01;P=0.041〈0.05）,联合治疗组mRS评分较高压氧组显著降低（P=0.025〈0.05）;治疗30 d后,与依达拉奉组比较,联合治疗组SSS评分均显著增高（P=0.000〈0.01）,mRS评分组显著降低（P=0.001〈0.01）,高压氧组mRS评分也较依达拉奉组显著降低（P=0.009〈0.01）;治疗90 d后,与高压氧组和依达拉奉组比较,联合治疗组SSS评分显著增高（P=0.000〈0.01;P=0.000〈0.01）,mRS评分显著降低（P=0.000〈0.01;P=0.000〈0.01）。结论微创血肿清除术后对高血压脑出血患者早期行高压氧联合依达拉奉治疗能显著改善预后。

Effect of Hyperbaric Oxygen Therapy Combined with Edaravone on Patients with Hypertensive Cerebral Hemorrhage after Micro-invasive Evacuation of Hematoma

Objective To investigate the clinical effects of the hyperbaric oxygen therapy(HBOT) combined with Edaravone on patients with hypertensive cerebral hemorrhage after micro-invasive evacuation of hematoma.Methods Two hundred and sixteen patients with hypertensive cerebral hemorrhage after micro-invasive evacuation of hematoma were randomly divided into combined treatment group(76 cases received HBOT and intravenous infusion of Edaravone),HBOT group(66 cases received HBOT) and Edaravone group(74 cases received...