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手足口病患儿病情轻重及预后的目标性监测研究
引用本文:裴旭东,翟玉峰,张怀宏.手足口病患儿病情轻重及预后的目标性监测研究[J].实用全科医学,2011(8):1185-1186.
作者姓名:裴旭东  翟玉峰  张怀宏
作者单位:河南省南阳市中心医院感染肝病科;
摘    要:目的探讨血糖、白细胞计数及血浆C反应蛋白(hs—CRP)测定对手足口病患儿病情和预后判断的价值。方法432例手足口病患儿(治疗组),其中包含普通型234例,发热重型198例。于入院时和治疗3d、7d后分别检测空腹血糖、全血白细胞计数和hs—CRP水平,并与322例健康体检者(对照组)比较。结果入院时观察组血糖、白细胞计数、hs—CRP水平均明显高于对照组(P均〈0.05),hs-CRP阳性率明显高于血糖阳性率及白细胞数阳性率(P〈0.05);其中重型患儿空腹血糖水平显著高于对照组(P〈0.05),而普通型与对照组比较无显著差异。治疗3d后观察组hs-CRP、白细胞计数水平均明显下降;其中重型患儿明显降低(P〈0.05)。治疗7d后观察组血糖、白细胞计数水平均明显下降;其中重型患儿明显降低(P〈0.01)。Pearson相关分析示病情严重程度与空腹血糖和白细胞计数水平均呈正相关,与hs—CRP水平无明显相关性。结论hs—CRP可作为手足口病早期诊断和指导临床用药的敏感指标,而血糖和白细胞计数可作为判断病情和预后的主要参考指标。

关 键 词:手足口病  血糖  C一反应蛋白  白细胞计数

Objective Monitoring of Severe Extent and Prognosis in Children with Hand Foot and Mouth Disease
PEI Xu-dong,ZHAI Yu-feng,ZHANG Huai-hong.Infectious Liver Dieases.Objective Monitoring of Severe Extent and Prognosis in Children with Hand Foot and Mouth Disease[J].Applied Journal Of General Practice,2011(8):1185-1186.
Authors:PEI Xu-dong  ZHAI Yu-feng  ZHANG Huai-hongInfectious Liver Dieases
Institution:PEI Xu-dong,ZHAI Yu-feng,ZHANG Huai-hong.Infectious Liver Dieases Department,Nanyang Central Hospital,Nanyang 473000,He'nan,China
Abstract:Objective To investigate the value of detecting blood sugar,lencocyte count and hs-CRP Levels in the judgment of the severe extent and prognosis in children with hand-foot-mouth disease(HFMD).Methods The levels of blood sugar,Lencocyte count and hs-CRP of 432 children with HFMD(the treatment group,including 234 common type cases and 198 severe cases with fever) and 322 healthy cases(the control group) were detected on 0d,3d,7d of treatment.Results The levels of blood sugar,lencocyte count and hs-CRP of the ...
Keywords:Hand foot and mouth disease  Blood sugar  C-reactive protein  Lencocyte count  
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