绝经后应用小剂量利维爱妇女血浆蛋白、血糖和血脂的变化

目的：观察绝经后应用小剂量利缩爱妇女血浆蛋白、血糖和血脂的变化。方法：检测６０例妇女用药３，６，１２和２４个月时的血浆白蛋白（Ａ）、球蛋白（Ｇ）、血糖（ＧＬ）、总胆固醇（ＴＣ）、甘油三脂（ＴＧ）、高密度脂蛋白（ＨＤＬ）和低密度脂蛋白（ＬＤＬ），结果：用药６个月时Ａ升高，以１２个月时升高最明显（Ｐ〈０．０１）。用药３个月后ＴＧ显著降低（Ｐ〈０．０５～０．０１），ＨＤＬ用药３个月时有所降低（Ｐ〉０．０１），以后渐恢复至用药前水平。用药后Ｇ、ＧＬ、ＴＣ、ＬＤＬ无明显变化，但ＧＬ、ＴＣ降低的妇女多于升高者。结论：小剂量利维爱可使绝经后妇女Ａ升高，明显降低ＴＧ，对Ｇ、ＧＬ、ＴＣ、ＨＤＬ、ＬＤＬ无明显影响。

CHANGES OF PLASMA PROTEIN, GLUCOSE AND BLOOD-LIPID WITH USE OF LOW DOSAGE LIVIAL IN POSTMENOPAUSAL WOMEN

Objective: To observe the changes of plasma protein, glucose and blood-lipid with use of low dosage livial in postmenopausal women. Methods: Plasma albumin (A),globulin (G), glucose (GL), total cholesterol (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL) were detected in 60 cases after 3,6,12 and 24 month respectively. Results: After dosing 6 month A was elevated, but most significantly in dosing 12 month ( P <0.01). TG was markedly lowered after dosing 3 month ( P <0.05~0.01). After dosing 3 month HDL was slight lowered, but returned to normal gradually. After dosing G, GL, TC and LDL weren't markedly changes. Conclusions: With use of low dosage livial A elevated, TG lowered significantly, but there weren't markedly influence for G, GL, TC, HDL and LDL in postmenopausal women.