新型隐球菌性脑膜炎的实验室诊断

目的 探讨新型隐球菌性脑膜炎的实验室诊断方法 .方法 对脑脊液标本进行墨汁染色镜检,查找新型隐球菌.结果 13例新型隐球菌性脑膜炎患者的脑脊液标本均镜检到新型隐球菌,而对照组未镜检出一例阳性.结论 因新型隐球菌性脑膜炎的临床表现与结核性脑膜炎很相似,实验室几乎均未将墨汁染色镜检新型隐球菌作为脑脊液的常规检测项目,故新型隐球菌性脑膜炎往往不能及时确定而被误诊.对脑脊液标本进行墨汁染色镜检,是诊断新型隐球菌性脑膜炎的非常有效的方法 ,应将墨汁染色镜检新型隐球菌作为脑脊液的常规检测项目而日常开展.

A Research Report on the Laboratory Diagnosis of Cryptococcus Meningitis

Objective To understand the causes of misdiagnosion and study the methods of diagnosis for Cryptococcus neoformansis meningitis.Methods Cerebrospinal fluid (CSF) was stained by black ink, then them were detected with microscope to look for Cryptococcus neoformans.Results 13 patients with Cryptococcus neoformansis meningitis were all detected Cryptococcus neoformans in CSF. The control cases were all negative results to apply the same method.Conclusion The causes of misdiagnosis for Cryptococcus neoformansis meningitis are very much alike both Cryptococcus neoformansis meningitis and tuberculosis meningitis, and the method do not apply in routine CSF test for CSF be stained by black ink. It is a very much useful method on CSF is stained by black ink for detection of Cryptococcus neoformans. The method ought to apply in routine CSF test.