| 低分子量肝素在血液透析中的应用 |
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| 引用本文： | 潘健涛,叶家雄.低分子量肝素在血液透析中的应用[J].中华泌尿外科杂志,1997,18(7):430-432. |
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| 作者姓名： | 潘健涛 叶家雄 |
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| 作者单位： | 中山医科大学附属第一医院肾内科(潘健涛)，澳门镜湖医院肾科(叶家雄) |
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| 摘 要： | 为探讨低分子量肝素在血液透析中的抗凝作用，选择血液透析患者６０例、１５００例次，分成两组。一组透析中使用肝素抗凝，另一组使用低分子量肝素（ＣＸ）抗凝，分别测量凝血时间、凝血酶原时间、活化部分凝血活酶时间及血小板，进行对照研究。结果发现，ＣＸ比肝素能更有效地抗凝，又能减少出血倾向，透析器复用次数明显增加，活化部分凝血活酶时间降低（Ｐ＜０．０１）。表明低分子量肝素特别适用于有出血倾向者，可代替肝素在血液透析中应用。
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| 关 键 词： | 血液透析 低分子量肝素 |
The use of low molecular weight heparin in hemodialysis |
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| Pan Jiantao,Ye Jiaxiong.Deapartment of Nephrology,The First Affiliated Hospital,Sun Yatsen University of Medical Scineces,Guangzhou.The use of low molecular weight heparin in hemodialysis[J].Chinese Journal of Urology,1997,18(7):430-432. |
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| Authors: | Pan Jiantao Ye JiaxiongDeapartment of Nephrology The First Affiliated Hospital Sun Yatsen University of Medical Scineces Guangzhou |
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| Institution: | Pan Jiantao,Ye Jiaxiong.Deapartment of Nephrology,The First Affiliated Hospital,Sun Yatsen University of Medical Scineces,Guangzhou 510080 |
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| Abstract: | A comparative study between unfractionated heparin and low molecular weight heparin as the anticoagulant in hemolysis was carried out.60 chronic dialysis patients were divided into 2 groups,one with the use of unfractionated heparin and the other with low molecular weight heparin as the anticoagulant and CT,PT,APTT were measured.Low moecular weight heparin (clexane) was found to be more effective as an anticoagulant and hemorrhagic tendency has been less.With the use of clexane,the dialyzer could be more repea dedly used.APTT was decreased ( P <0.01).Clexane was particularly recommended for chronic hemodialysis patients with hemorrhagic tendency. |
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| Keywords: | Hemodialysis Low molecular weight heparin |
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