泰脂安胶囊对急性冠脉综合征患者炎症因子的影响

目的：观察泰脂安胶囊对急性冠脉综合征（ACS）患者血清炎症因子的影响。方法：收集72例ACS患者，随机分为氟伐他汀组（36例）和泰脂安组（36例。两组均予常规治疗。氟伐他汀组口服氟伐他汀40mg，天，泰脂安组口服泰脂安9粒，天。用酶联免疫吸附法分别检测两组患者治疗前后血浆C反应蛋白（CRP）、肿瘤坏死因子α（TNF—α）、白细胞介素6（IL-6）水平。结果：与治疗前相比。两组治疗后CRP、TNF—α和IL-6浓度显著下降（P〈0．05），氟伐他汀组CRP浓度下降较泰脂安组显著（P〈0.05），TNF-α和IL-6两组浓度下降程度比较无统计学意义（P〉0．05）。结论：泰脂安胶囊具有抗炎和稳定斑块的重要作用。

Taizhi'an capsule on patients with an acute coronary syndrome.The influence of proinflammatory factor

Objective：To observe the influence oftaizhian capsule on serum inflammatory factors in patients with acute coronary syn- drome（ACS）.Methods：Seventy two patientswith ACS were randomized into two groups：fluvastatin group（n=36）and taizhian group（n= 36）. Fluvastatin g~upweretreated withtluvastatin （40mg per day）androutine treatment.Taizhian group weretreated withtaizhian capsule （9 capsules per day）androutine treatment.The concentration of serum C-reactive protein （CRP）,tumor necrosis factor α （TNF- α）and interleukin 6（IL--6）were measured by enzyme-linked immunosorbent assay（EL1SA）.Resuhs：After treatment,the concentration of serum CRP,TNF-α and IL--6 were decreased significandy in two groups （P〈0.05）. CRP levels decreased significantly influvastatin group than taizhian group.（P〈0.05）, thedecline of TNF-α and IL-6 concentrationsin the two groups shows nosignificant difference （P〉0.05）. Conclusion：Taizhian capsule had effect on anti-inflammation and stabilizing atherosclerotic plaques.