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Aflibercept‐related nasal septum perforation
Authors:Ali Alkan  Levent Yücel  Dılşa Mızrak  Hakan Akbulut
Affiliation:1. Department of Medical Oncology, Ankara University School of Medicine, Ankara, Turkey;2. Department of Otolaryngology‐Head and Neck Surgery, Ankara University School of Medicine, Ankara, Turkey
Abstract:Hypertension, cytopenia and diarrhea are the most common side effects of aflibercept. Rarely thromboembolism, hemorrhage, fistulization and reversible posterior leukoencephalopathy have been reported. Here we report a patient experiencing nasal septum perforation during aflibercept therapy.
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