Impairment of emotional expression recognition in schizophrenia: A Cuban familial association study |
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| Authors: | Raúl Mendoza Yuranny Cabral-Calderin Mayelin Domínguez Alexander Garcia Mayelin Borrego Antonio Caballero Seidel Guerra Migdyrai Martín Reyes |
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| Institution: | 1. Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China;2. North China Electric Power University, Beijing, China;3. Faculty of Health Management, Guangzhou Medical University, Guangzhou, China;4. The University of Chinese Academy of Sciences, Beijing, China;5. School of Psychology, South China Normal University, Guangzhou, China, Center for Studies of Psychological Application, South China Normal University, Guangzhou, China;6. Shanghai Key Laboratory of Brain Functional Genomics (MOE & STCSM), School of Psychology and Cognitive Science, East China Normal University, China;7. Department of Psychology, the Chinese University of Hong Kong, Hong Kong Special Administrative Region, China;8. Castle Peak Hospital, Hong Kong Special Administrative Region, China;9. Departments of Psychology and Psychiatry, University of Wisconsin-Madison, USA;1. Queensland Brain Institute, The University of Queensland, Australia;2. Centre for Advanced Imaging, The University of Queensland, Australia;3. School of Mathematics and Physics, The University of Queensland, Australia;4. ARC Centre for Integrative Brain Function, Australia;1. Department of Psychology, Université du Québec à Montréal, Canada;2. Department of Psychology, Université du Québec à Chicoutimi, Canada |
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| Abstract: | It is well established that schizophrenia is associated with difficulties in recognizing facial emotional expressions, but few studies have reported the presence of this deficit among their unaffected relatives. This study attempts to add new evidence of familial association on an emotional expression processing test. The study evaluated the performance of 93 paranoid schizophrenia patients, 110 first-degree relatives of probands from multiplex schizophrenia families, and 109 nonpsychiatric controls on a facial emotional recognition test using a computer morphing technique to present the dynamic expressions. The task entailed the recognition of a set of facial expressions depicting the six basic emotions presented in 21 successive frames of increasing intensity. The findings indicated that schizophrenia patients were consistently impaired for the recognition of the six basic facial expressions. In contrast, their unaffected relatives showed a selective impairment for the recognition of disgust and fearful expressions. Familial association of selective facial emotional expressions processing deficit may further implicate promising new endophenotypes that can advance the understanding of affective deficits in schizophrenia. |
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