2型糖尿病患者糖化血红蛋白与血糖血脂间的相关性观察

目的探讨2型糖尿病患者糖化血红蛋白水平与血糖、血脂之间的关系。方法对糖尿病组及正常对照组同时测定糖化血红蛋白（HbAlc）、空腹血糖（FBG）、甘油三脂（TG）、总胆固醇（CH）、高密度脂蛋白（HDL-C）及低密度脂蛋白（LDL-C），对两组的检测结果进行比较，分析糖化血红蛋白与空腹血糖及各项检测是否具有相关性。结果2型糖尿病组的HbAlc、FBG、TG、CH及LDL。C明显高于健康对照组，HDL—C则低于健康对照组，差异有显著性（P〈0．05）。糖尿病组HbAlc与FBG，TG，CH，LDL-C各项结果的关系不明显。结论2型糖尿病患者血脂几率显著高于正常人，其血中HbAlc与FBG、TG存在正相关关系，与TC，HDL-C、LDL-C关系不明显。糖化血红蛋白与血糖、血脂同时检测在糖尿病的预防和治疗过程中有一定的参考价值。

The relationship between HbAIc and glucose and lipid in type I DM patients

Objective To observe the correlation between glycosylated hemoglobin(HbAlc) and blood glucose, serum lipids. Methods Measuring HbAlc、fasting blood glucose(FBG) and serum lipids(triglycerides, TG), total cholesterol(TC), high density lipoprotein(HDL) and low density lipoprotein(LDL) in 50 healthy subjects and 144 patients with diabetes mellitus(DM) observed in patients with HbAlc concentration effect on serum lipid levels. Results The levels of HbAlc, FBG, TG, CH, LDL-C in DM groups were obviously higher than those of healthy subjects, the level of HDL-C was lower than that of normal. HbAlc level showed positive correlation with FBG(0.457), and TG(0.262) respective. And with no obvise correlation with TC, LDL-C, HDL-c. Conclusion Diabetes with hyperlipidmia risk was higher than that of normal. There is a positive correlation between HbAlc and blood glucose, serum lipid. Glycosylated hemoglobin and blood glucose, blood lipids detection at the same time in prevention and treatment of diabetes has some reference value.