| 比阿培南对鲍曼不动杆菌的抗菌活性评价 |
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| 引用本文： | 赖艳榕,彭湘明,刘少娟,刘燕娣. 比阿培南对鲍曼不动杆菌的抗菌活性评价[J]. 中国医药导报, 2010, 7(33): 44-45 |
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| 作者姓名： | 赖艳榕 彭湘明 刘少娟 刘燕娣 |
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| 作者单位： | [1]广东省广州市红十字会医院检验科,广东广州510220 [2]广东医学院,广东东莞523808 |
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| 摘 要： | 目的：评价比阿培南对鲍曼不动杆菌的体外抗菌活性。方法：应用琼脂稀释法测定比阿培南、美罗培南、亚胺培南、头孢他啶对临床分离出的30株鲍曼不动杆菌的最低抑菌浓度（MIC）,并计算MIC50和MIC90。结果：比阿培南、美罗培南、亚胺培南、头孢他啶的MIC50分别为2、4、2、128μg/ml,MIC90分别为16、32、32μg/ml、512μg/ml,耐药率分别为20.0%、30.0%、33.3%、70.0%。结论：比阿培南与其他3种药物比较对鲍曼不动杆菌有更强的体外抗菌活性。
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| 关 键 词： | 比阿培南 鲍曼不动杆菌 抗菌活性 |
The evaluation of antibacterial activity of Biapenem against Acinetobacter baumannii in vitro |
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| LAI Yanrong,PENG Xiangming,LIU Shaojuan,LIU Yandi. The evaluation of antibacterial activity of Biapenem against Acinetobacter baumannii in vitro[J]. China Medical Herald, 2010, 7(33): 44-45 |
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| Authors: | LAI Yanrong PENG Xiangming LIU Shaojuan LIU Yandi |
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| Affiliation: | 1.Clinical Laboratory of Guangzhou Red Cross Hospital,Guangzhou 510220,China;2.Guangdong Medical University,Dongguan 523808,China) |
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| Abstract: | Objective：To evaluate the antibacterial activity of Biapenen on Acinetobacter baumannii in vitro.Methods：The MICs of Biapenem,Meropenem,Imipenem and Ceftazidime were tested by agar dilution method on 30 selected Acine tobacter baumannii strains.And then compared them.Results：The MIC50 of Biapenem,Meropenem,Imipenem were 2,4,2,128 μg/ml and the MIC90 of them were 16,32,32 μg/ml,512 μg/ml.The resistance rates were as follows：20.0%,30.0%,33.3%,70.0%.Conclusion：The antibacterial activity of Biapenem on Acinetobacter baumannii in vitro is stronger than the other 3 kinds of drugs. |
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| Keywords: | Biapenem Acinetobacter baumannii Antibacterial activity |
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