A case in which danaparoid sodium was effective for portal venous thrombosis developed after endoscopic injection sclerotherapy for esophageal varices |
| |
Authors: | Ryushi Shudo Yasuyuki Yazaki Mitsunori Honda Kenji Sugawara |
| |
Affiliation: | (1) Department of Gastroenterology, Kurosawa Hospital, 4-1 Odori Minami, Obihiro 080-0010, Japan;(2) Digestive Disease Center, Kobayashi Hospital, Kitami, Japan;(3) Kitami Digestive Clinic, Kitami, Japan |
| |
Abstract: | We report a case of hepatitis C type liver cirrhosis with portal venous thrombosis in which danaparoid sodium was very effective. The patient developed portal venous thrombosis, esophageal ulcer, and esophageal stenosis at the same time after sclerotherapy. Since it was confirmed by abdominal computed tomography that there was no portal venous thrombosis before sclerotherapy, development of the thrombosis was considered to be associated with sclerotherapy. The patient was treated with balloon dilation therapy for esophageal stenosis, and with anticoagulation therapy using danaparoid sodium for portal venous thrombosis. The portal venous thrombosis disappeared 4 weeks after the treatment. Despite the condition of esophageal ulcer being caused by sclerotherapy, the patient was safely treated without any adverse effects and complications, and the clinical course has been good. It was indicated that danaparoid sodium was an anticoagulant unlikely to cause adverse effects such as hemorrhage and might be an effective drug for treatment of portal venous thrombosis. |
| |
Keywords: | Endoscopic injection sclerotherapy Portal venous thrombosis Danaparoid sodium |
本文献已被 SpringerLink 等数据库收录! |
|