| 慢性肺源性心脏病病人血流动力学研究及硝苯吡啶对其影响 |
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| 引用本文： | 吴为群 容中生. 慢性肺源性心脏病病人血流动力学研究及硝苯吡啶对其影响[J]. 中华内科杂志, 1994, 33(1): 21-23 |
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| 作者姓名： | 吴为群 容中生 |
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| 作者单位： | 中山医科大学附属第一医院内科 |
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| 摘 要： | １０例慢性肺心病人行Ｓｗａｎ－Ｇａｎｚ导管检查，同时行血气分析以及肺功能、超声心动图等检查，并观察了舌下含服硝苯吡啶对血流动力学等参数的影响。结果显示肺动脉压（ＰＡＰ）等血流动力学参数与ＰａＯ＿２等参数呈显著相关，ＰａＯ＿２等可能是预计ＰＡＰ的有用参数。持续吸氧，纠正低氧血症，有利于防治肺动脉高压。舌下含服硝苯吡啶后ＰａＯ＿２显著降低，肺内生理分流增加，体循环血压显著下降，但ＰＡＰ未降低。故不宜长期使用硝苯吡啶舌下含服治疗肺心病和肺动脉高压。
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| 关 键 词： | 肺心病，血液动力学，硝苯吡啶 |
HEMODYNAMIC STUDIES OF PULMONARY HEART DISEASES AND THE EFFECTS OF NIFEDIPINE |
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| WuWen-pun,Rong Zhong-sheng,Yang Xi-qiang. HEMODYNAMIC STUDIES OF PULMONARY HEART DISEASES AND THE EFFECTS OF NIFEDIPINE[J]. Chinese journal of internal medicine, 1994, 33(1): 21-23 |
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| Authors: | WuWen-pun Rong Zhong-sheng Yang Xi-qiang |
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| Affiliation: | WuWen-pun,Rong Zhong-sheng,Yang Xi-qiang.the First Affiliated Hospital of Sun Yat-sen University of Medical Scicnces. Guangzhou,510080 |
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| Abstract: | wan-Ganz catherization blood gas analysis,pulmonary function tests and two-dimensional echocardiography were perfoimed in 10 patients with pulmonary heart disease and the effects of nifedipine were then observed.Mean pulmonary artery pressure (mPAP)correlated significantly to PaO_2.PaO_2 may be a useful parameter for predicting mPAP. Continuous oxygen breathing can correct hypoxemia,prevent and alleviate pulmonary artery hypertension(PAH).After using nifedipine,PaO_2 and blood pressure of systemic circulation decreased significantly, while pulmonary physiological shunt increased and pulmonary artery pressure did not decrease. As a consequence,the use of nifedipine to treat pulmonary heart disease and PAH is not advocated. |
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| Keywords: | Pulmonary heart disease Hemodynamics Nifedipine |
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