胆道闭锁和新生儿肝炎肝脏的电镜观察

对6例胆道闭锁患儿和3例新生儿肝炎患儿肝脏进行了透射电镜的观察。发现胆道闭锁患儿肝细胞质内高电子密度物质(EDM)较新生儿肝炎患儿为多。认为其与胆汁淤滞有密切关系。推测其为胆色素性物质。胆道闭锁患儿毛细胆管数量较新生儿肝炎患儿为多,管腔稍有扩张。还可见到胆道闭锁患儿毛细胆管处细胞连接破坏现象。这些可能是胆管梗阻,胆管内压增高所致。

THE ELECTRON MICROSCOPIC STUDY OF THE LIVER BILIARY ATRESIA AND NEONATAL HEPATITIS

Different results in five structure study of the liver of biliary atresia and neonatal hepatitis were reported. 6 cases of biliary atresia ard 3 of n(?)natal hepatitis were studied with transmission electron mierescope. The electron dense material (EDM) in the hepat(?)ellular plasma of biliary atresia was more than that of neonatal hepatitis. The EDM was considered to be closely related to cholestasis and inferred as bile pigment material. The canaliculi of biliary atresia were more than those of neonatal hepatitis. The lumen of the canaliculi of oiliary atreisa (?)nlarged slightly. The bro(?)n jun(?)tional complex nearby the canaliculus in biliary atreisa could be found. These might be caused by the higher pressure in bile duct due to the obstruetion. In both of the diseases the microvilli were normal and the b(?)n might (?) from the degeneration of the liver cell.