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直角边缘囊袋张力环预防兔后囊膜混浊的实验研究
引用本文:石海红,吴坚,杨铃.直角边缘囊袋张力环预防兔后囊膜混浊的实验研究[J].国际眼科杂志,2013,13(9):1762-1764.
作者姓名:石海红  吴坚  杨铃
作者单位:中国江苏省南通市,南通大学附属医院眼科;中国江苏省南通市,南通大学附属医院眼科;中国江苏省南通市,南通大学附属医院眼科
摘    要:目的:探讨直角边缘囊袋张力环(capsule tension ring,CTR)预防兔后囊膜混浊(posterior capsule opacification,PCO)的作用。方法:新西兰兔20只随机分为两组,进行超声乳化晶状体摘除术后,实验组植入CTR和CraneOV-55C人工晶状体(intraocular lens,IOL),对照组只植入CraneOV-55CIOL。观察术后并发症和PCO情况。术后3mo行光镜和透射电镜检查,观察晶状体后囊膜的形态学变化。结果:术后3mo实验组和对照组都发生了明显的PCO(P>0.05),各组Soemmering环形成程度无统计学差异(P>0.05)。病理学检查发现,两组兔赤道部晶状体上皮细胞增生形成了巨大的Soemmering环,大量晶状体上皮细胞移行至后囊膜。结论:直角边缘CTR未能预防兔PCO的发生,有必要对其进一步改进。

关 键 词:后囊膜混浊  囊袋张力环  
收稿时间:2013/4/16 0:00:00
修稿时间:2013/8/18 0:00:00

Preventive effect of sharp-edged capsule tension ring on posterior capsule opacification
Hai-Hong Shi,Jian Wu and Ling Yang.Preventive effect of sharp-edged capsule tension ring on posterior capsule opacification[J].International Journal of Ophthalmology,2013,13(9):1762-1764.
Authors:Hai-Hong Shi  Jian Wu and Ling Yang
Institution:Department of Ophthalmology, the Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China;Department of Ophthalmology, the Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China;Department of Ophthalmology, the Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China
Abstract:AIM: To evaluate the effect of sharp-edged capsule tension ring(CTR)on posterior capsule opacification(PCO).

METHODS: Twenty eyes of New Zealand white rabbits were randomly divided into two groups. After phacoemulsification, the experimental group was implanted with CTR and Crane OV-55C intraocular lens(IOL), and the control group was implanted with Crane OV-55C IOL only. Complications and PCO were observed by slit lamp microscope. Three months after surgery, light microscope and transmission electron microscope examinations were performed.

RESULTS: There was no statistically significant difference between the experimental group and the control group about PCO and Soemmering's ring formation(P>0.05). Pathological evaluations revealed lens epithelial cells(LECs)accumulated at the equatorial capsule forming a large Soemmering's ring and abundant LECs were migrated onto the posterior capsule forming a thick layer in both experimental group and the control group.

CONCLUSION: Sharp-edged CTR fail to retard PCO formation and development in rabbits and it is nessessary to improve it.

Keywords:posterior capsule opacification  capsule tension ring  rabbit
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