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血管内超声指导下对小血管病变的介入治疗
引用本文:张建起,石蕊,王燕,姜铁民,李玉明.血管内超声指导下对小血管病变的介入治疗[J].中华老年心脑血管病杂志,2014(6).
作者姓名:张建起  石蕊  王燕  姜铁民  李玉明
作者单位:天津医科大学研究生院;武警后勤学院附属医院心脏医院;
摘    要:目的评价血管内超声(IVUS)对小血管病变介入治疗的临床意义。方法回顾性分析2010年10月2013年2月于我院接受介入治疗的单支小血管(≤2.5mm)病变患者共237例,其中,IVUS指导下介入治疗的患者105例(Ⅰ组),冠状动脉造影(CAG)指导下介入治疗的患者132例(Ⅱ组)。分析2组患者基线资料、病变特点、介入治疗及随访期间心脏不良事件和再狭窄情况。结果 2组患者介入治疗均成功,Ⅰ组和Ⅱ组置入支架直径(2.50±0.40)mmvs(2.34±0.37)mm]、支架长度(28.75±7.77)mmvs(35.78±10.45)mm]、支架高压后扩张(91.4%vs55.3%)和支架内再狭窄(1.9%vs 7.6%)比较,差异有统计学意义(P=0.002,P=0.000,P=0.000,P=0.042);2组串联支架、CAG随访比较差异无统计学意义(P>0.05)。2组患者住院及随访1、3和6个月期间,均无主要不良心脏事件发生。结论对于小血管病变的介入治疗,IVUS具有较好的指导作用。

关 键 词:超声检查  介入性  冠状血管造影术  支架  冠状动脉再狭窄

Intravascular ultrasonography-guided intervention therapy for small vessel lesions
Abstract:Objective To assess the clinical significance of intravascular ultrasonography(IVUS)-guided intervention therapy for small vessel lesions.Methords Two hundred and thirty-seven patients who underwent intervention therapy for single vessel(≤2.5mm)lesions in our hospital from October 2010to February 2013were divided into IVUS-guided intervention therapy group(n=105)and coronary ateriography-guided group(n=132).Their baseline parameters,lesion features,main adverse cardiac events(MACE)and restenosis during follow-up were analyzed.Results Intervention therapy for the two groups was successful.The diameter,length,dilation and restenosis of stents were significantly different between the two groups(P=0.002,P= 0.000,P=0.000,P=0.042).However,no significant difference was found in the incidence of series stent and MACE during follow-up(P>0.05).Conclusion IVUS plays an important role in intervention therapy for small vessel lesions.
Keywords:ultrasonography  interventional  coronary angiography  stents  coronary restenosis
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