扩张型心肌病患者心外膜脂肪厚度与左心室重构的相关性

目的研究扩张型心肌病(DCM)患者心外膜脂肪厚度与左心室重构及左心室功能不全的关系。方法收集DCM患者120例(DCM组)和健康体检者76例(对照组),应用常规心脏超声测量左心室收缩末内径(LVESD)、左心室舒张末内径(LVEDD)、左心室收缩末容积(LVESV)、左心室舒张末容积(LVEDV)、左心室收缩末容积指数(LVESVI)、左心室舒张末容积指数(LVEDVI)、左心室收缩末球形指数(SIs)、左心室舒张末球形指数(SId)、LVEF、心外膜脂肪厚度等,比较2组各超声指标的关系。结果 DCM组LVESD(53.0±9.6)mmvs(33.2±4.5)mm]、LVEDD(68.5±9.3)mmvs(38.3±3.0)mm]、LVESV(79.5±13.6)ml vs(42.0±10.5)ml]、LVEDV(165.0±18.6)ml vs(98.2±14.0)ml]、LVESVI(49.2±10.7)ml/m2 vs(30.6±9.6)ml/m2]、LVEDVI(101.8±10.0)ml/m2 vs(61.4±9.0)ml/m2]较对照组明显增高,LVEF(31.5±7.2)%vs(64.9±6.4)%]、SIs(1.3±0.2)vs(2.0±0.3)]、SId(1.3±0.2)vs(1.8±0.2)]和心外膜脂肪厚度(4.9±1.1)mmvs(7.8±2.0)mm]较对照组明显降低(P<0.05)。DCM组心外膜脂肪厚度与LVESD、LVEDD、LVESV、LVEDV、LVEDVI、LVESVI、SIs、SId呈正相关(P<0.05)。结论 DCM患者的心外膜脂肪厚度与左心室重构明显相关,与左心室功能不全无相关性。

Relation between epicardial adipose tissue thickness and left ventricular remodeling in dilated cardiomyopathy patients

Objective To study the relation of epicardial adipose tissue(EAT)thickness with left ventricular remodeling and dysfunction in dilated cardiomyopathy(DCM)patients.Methods One hundred and twenty DCM patients served as a DCM group and 76healthy subjects undergoing physical examination served as a control group.Their left ventricular end-diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),left ventricular end diastolic volume(LVESV),left ventricular end systolic volume(LVEDV),left ventricular end diastolic volume index(LVEDVI),left ventricular end systolic volume index(LVESVI),sphericity index(SI),left ventricular ejection fraction(LVEF),and EAT thickness were measured by routine cardiac ultrasonography.Results The LVESD,LVEDD,LVESV,LVEDV,LVESVI,LVEDVI were significantly higher while the LVEF,SIs,SIdand EAT thickness were significantly lower in DCM group than in control group(P<0.05).Linear correlation analysis showed that the EAT thickness was positively related with the LVESD,LVEDD,LVESV,LVEDV,LVESVI,LVEDVI,SIsand SId(P<0.05).Conclusion The EAT thickness is significantly related with the left ventricular remodeling but not related with the left ventricular dysfunction in DCM patients.