Aglacins I-K, three highly methoxylated lignans from Aglaia cordata |
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Authors: | Wang Bin-Gui Ebel Rainer Wang Chang-Yun Edrada Ru Angelie Wray Victor Proksch Peter |
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Affiliation: | Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, People's Republic of China. wangbg@ms.qdio.ac.cn |
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Abstract: | Further chemical investigation of the stem bark of Aglaia cordata has led to the isolation and identification of three new lignans, namely, aglacins I-K (1-3), all of which contain two contiguous trimethoxylated phenyl systems. Among them, aglacins I and J (1 and 2) are new members of the aryltetralin cyclic lactol class, while aglacin K (3) is a new example of tetrahydrofuran lignan. The structures of these compounds were established on the basis of spectroscopic data interpretation. |
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