| 胆胰管汇合异常与胆囊癌的关系 |
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| 引用本文： | 周彦明,杨甲梅. 胆胰管汇合异常与胆囊癌的关系[J]. 中国普外基础与临床杂志, 2005, 12(4): 361-364 |
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| 作者姓名： | 周彦明 杨甲梅 |
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| 作者单位： | 第二军医大学东方肝胆外科医院,上海,200438 |
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| 摘 要： | 目的探讨胆胰管汇合异常(anomalous pancreaticobiliary ductal junction，APBDJ)与胆囊癌的关系。方法复习相关文献。结果APBDJ与胆囊癌的发生密切相关，胰液的自由返流及胆囊上皮细胞分子生物学的改变可能是重要的癌变机理。结论APBDJ是胆囊癌的高危因素，建议APBDJ患者应作预防性胆囊切除。
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| 关 键 词： | 胆胰管汇合异常 胆囊癌 |
| 文章编号： | 1007-9424(2005)04-0361-04 |
| 修稿时间： | 2004-12-21 |
Relationship Between Anomalous Pancreaticobiliary Ductal Junction and Gallbladder Carcinoma |
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| ZHOU Yan-ming,YANG Jia-mei. Relationship Between Anomalous Pancreaticobiliary Ductal Junction and Gallbladder Carcinoma[J]. Chinese Journal of Bases and Clinics In General Surgery, 2005, 12(4): 361-364 |
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| Authors: | ZHOU Yan-ming YANG Jia-mei |
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| Affiliation: | ZHOU Yan-ming,YANG Jia-mei. Eastern Hepatobiliry Surgery Hospital,Second Military Medical University,Shanghai 200438,China |
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| Abstract: | Objective To explore the relationship between anomalous pancreaticobiliary ductal junction(APBDJ) and gallbladder carcinoma. Methods The current related literatures were reviewed.Results APBDJ was associated with gallbladder carcinoma development. A proposed mechanism was free reflux of pancreatic juice into the gallbladder and molecular alterations of gallbladder epithelial cells.Conclusion APBDJ is a high risk factor for gallbladder carcinoma. Prophylactic cholecystectomy is recommended for patients with APBDJ. |
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| Keywords: | Anomalous pancreaticobiliary ductal junction Gallbladder carcinoma |
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