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均匀设计法优选通心舒颗粒中药材的提取工艺
引用本文:刘 弘,王俊杰.均匀设计法优选通心舒颗粒中药材的提取工艺[J].中国药房,2014(11):1014-1016.
作者姓名:刘 弘  王俊杰
作者单位:解放军第152中心医院,河南平顶山467000
摘    要:目的:优选通心舒颗粒中药材的提取工艺。方法:以加水倍数、浸泡时间、提取时间、提取次数为考察因素,以提取液中丹酚酸B转移率、芍药苷转移率及干膏得率为评价指标,采用均匀设计法优选工艺。结果:最优提取工艺为加9倍量的水,浸泡20min,提取3次,每次105 min。结论:优选的工艺简便、易行,稳定性好,可用于通心舒颗粒中药材的提取。

关 键 词:均匀设计  提取工艺  层次分析加权法  回归分析

Optimization of the Extraction Technology of Medicinal Material from Tongxinshu Granules by Uniform Design
LIU Hong,WANG Jun-jie.Optimization of the Extraction Technology of Medicinal Material from Tongxinshu Granules by Uniform Design[J].China Pharmacy,2014(11):1014-1016.
Authors:LIU Hong  WANG Jun-jie
Institution:(No.152 Central Hospital of PLA, Henan Pingdingshan 467000, China)
Abstract:OBJECTIVE : To optimize the extraction technology of medicinal material from Tongxinshu granules. METHODS : The extraction technology was optimized by uniform design with the amount of water, soaking time, extraction time and extraction times as factors using transfer rate of salvianolic acid B and paeoniflorin and yield of dry extract as index. RESULTS: Optimized technology was as follows: 9-fold water, soaking for 20 min, extracting for 3 times, 105 min per time. CONCLUSIONS: The pre- ferred process is simple, easy, stable and suitable for the extraction of Tongxinshu granules.
Keywords:Uniform design  Extraction technology  AHP  Regression analysis
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