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精神分裂症患者血清唾液酸含量研究
引用本文:冯春霞,董占华,杜志广.精神分裂症患者血清唾液酸含量研究[J].临床精神医学杂志,2004,14(4):219-220.
作者姓名:冯春霞  董占华  杜志广
作者单位:256612,山东滨州市复退军人医院
摘    要:目的:探讨精神分裂症患者血清唾液酸(SA)含量的变化及其临床意义。方法:86例首发精神分裂症患者用利培酮治疗6个月,于治疗前及治疗第1、3、6个月末采取血液标本进行血清SA含量测定,同时用阳性与阴性症状量表(PANSS)评定疗效,并与32名健康者(正常对照组)进行比较。结果:精神分裂症患者血清SA含量明显高于对照组。治疗后逐渐下降,到第6个月末最明显,且与PANSS总分的降低值呈显著正相关。结论:精神分裂症患者发病期间血清SA含量增高,可能与精神病理学改变有关。

关 键 词:精神分裂症  唾液酸
文章编号:1005-3220(2004)04-0219-02
修稿时间:2004年1月9日

A correlative study of blood saliva acid levels and clinical effects in patients with schizophrenia
FENG Chun-xia,DONG Zhan-hua,DU Zhi-guang.Binzhou Demobilized Soldiers Hospital,Shandong.A correlative study of blood saliva acid levels and clinical effects in patients with schizophrenia[J].Journal of Clinical Psychological Medicine,2004,14(4):219-220.
Authors:FENG Chun-xia  DONG Zhan-hua  DU Zhi-guangBinzhou Demobilized Soldiers Hospital  Shandong
Institution:FENG Chun-xia,DONG Zhan-hua,DU Zhi-guang.Binzhou Demobilized Soldiers Hospital,Shandong 256612
Abstract:Objective:To explore the relationship between the blood saliva acid (SA) levels and clinical effects in patients with schizophrenia. Method:86 patients who met the CCMD-3 for schizophrenia were treated with risperidone for 6 months.The blood SA levels were tested and the clinical effects were rated with PANSS before and after treatment 1,3 and 6 months.32 normal controls were included in the study. Results:The blood SA levels were significantly higher in the study group than in the normal controls,and reduced gradually after treatment. There was significant positive correlation between the blood SA levels and the PANSS rating scores. Conclusion:The blood SA levels may be higher in patients with schizophrenia.
Keywords:Schizophrenia  Saliva acid
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