Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp |
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| Authors: | Tanaka Chiaki Yamamoto Yumiko Otsuka Masahito Tanaka Junichi Ichiba Toshio Marriott Gerard Rachmat Rachmaniar Higa Tatsuo |
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| Institution: | Department of Chemistry, Biology, and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan. |
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| Abstract: | Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance. |
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