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血浆ET和CGRP与高血压左室肥厚的关系研究现状
引用本文:闫丽梅,赵兴胜.血浆ET和CGRP与高血压左室肥厚的关系研究现状[J].内蒙古医学杂志,2007,39(5):586-588.
作者姓名:闫丽梅  赵兴胜
作者单位:1. 内蒙古医学院,内蒙古,呼和浩特,010059
2. 内蒙古自治区医院心内科,内蒙古,呼和浩特,010017
摘    要:目的:探讨高血压左室肥厚与血浆ET和CGRP的关系的研究现状。方法:阅读国内外大量相关文献,加以归纳总结,得出结论。结果:血浆ET可能是一种促高血压左室肥厚因子,CGRP可能是一种抗高血压左室肥厚因子。结论:左室肥厚是高血压病人左室重构的重要表现,是发生心、脑血管事件的一个独立危险因素,逆转LVH成为抗高血压治疗的重要目标,通过某种途径使血浆ET浓度下降和CGRP浓度的升高,可能有助于高血压与高血压左室肥厚的治疗。

关 键 词:内皮素  降钙素基因相关肽  高血压左室肥厚
文章编号:1004-0951(2007)05-0586-03
修稿时间:2006-10-21

Investigating Conditions of Plasma Endothelin, Calcitonin Gene- related Peptide and LVH
Gene- related Peptide and LVH.Investigating Conditions of Plasma Endothelin, Calcitonin Gene- related Peptide and LVH[J].Inner Mongolia Medical Journal,2007,39(5):586-588.
Authors:Gene- related Peptide and LVH
Institution:1. Postgraduate class 2004, Inner Mongolia Medical College, Huhhot 010059, China; 2. Department of Cardiovasology , Inner Mongolia Hospital, Huhhot 010017, China
Abstract:Objective:To explore the relationship between changes of plasma endothelin(ET),Calcitonin gene-related peptide(CGRP)levels and left ventricular hypertrophy(LVH)in patients with essential hypertension(EH).Method: Look up and summarize a great of relevant documents,draw a conclusion.Results: plasma ET may induce EH,plasma CGRP may relieve EH.Conclusions: LVH is risky factor of appearing complication for patients with EH,changing LVH is becoming a significant aim to cure EH,lowering the levels of plasma ET and increasing the levels of CGRP may be benefit to cure EH and LVH.
Keywords:Endothelin  Calcitonin gene- related pcptide  Left ventricular hypertrophy
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