泌尿生殖道感染患者的支原体检出情况及药敏分析

目的探讨2008年我院性病和妇科门诊就诊患者的泌尿生殖道支原体感染情况并分析药敏试验结果，为临床治疗支原体感染的抗生素选择提供依据。方法对诊断为宫颈炎、阴道炎和非淋菌性尿道炎的643例患者的宫颈或尿道分泌物，以培养-药敏一步法进行支原体检测与分析。结果共检出支原体的271例（42．2％），其中解脲支原体（Uu）186株，占68．6％；人型支原体（Mh）4株，占1．5％；Uu合并Mh感染81例，占29．9％；女性173例（63．8％），男性98例（36.2％）。9种抗生素中Uu和Mh对美满霉素、强力霉素和交沙霉素的敏感性好，Uu合并Mh感染对抗菌药物的耐药率明显升高。结论治疗泌尿生殖道支原体感染应根据药敏试验结果选用抗生素。

Mycoplasma detection status and the drug sensitivity test in the genitourinary tract infection patients

Objective To investigate the genitourinary tract mycoplasma infection status in the genitourinary tract and gynecology out-patient clinic, then the susceptibility test were applied, and to provide the basis for antibiotics selection. Methods Cervix or urethral secretions were obtained from 643 patients with cervicitis, vaginitis, or nongonococcal urethritis, the mycoplasma detection was achieved by culture-susceptibility test. Results 271 cases were infected with mycoplasma （42.2%）, in which 186 were mycoplasma urealytium （Uu, 68.6%）, 4 were human mycoplasma type （Mh, 1.5%）, 81 cases were combined infected （29.9%）; 173 patients were female （63.8%）, and 98 were male （36.2%）. Uu and Mh were sensitive to minocycline, deoxycycline and josamycin. The combined infection were more resistant to antibacterials. Conclusions Antibiotics for genitourinary tract mycoplasma infection should be selected according to the drug susceptibility test.