| 2013年宿州市748例喹喏酮类药物不良反应分析 |
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| 引用本文： | 郭秀秀.2013年宿州市748例喹喏酮类药物不良反应分析[J].北方药学,2014,0(7):112-113. |
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| 作者姓名： | 郭秀秀 |
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| 作者单位： | 郭秀秀(宿州市食品药品检验所 宿州 234000)； |
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| 摘 要： | 目的：研究影响喹诺酮类药物不良反应的因素，以期减少药物不良反应。方法：收集宿州市2013年喹诺酮类合成抗菌药物不良反应报表进行汇总分析。结果：748例喹诺酮类药物不良反应报表以左氧氟沙星引起的不良反应最多（68.14%）。不良反应涉及器官或系统最主要表现在胃肠系统（42.80%）、皮肤（30.64%）、中枢及外周神经系统（5.73%）。结论：应加强喹诺酮类药物的临床监测，提高合理用药的安全性。
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| 关 键 词： | 喹诺酮类 药物不良反应 合成抗菌药 |
Analysis of 748 cases of quinolone adverse drug reaction in Suzhou city of 2013 |
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| Guo Xiuxiu.Analysis of 748 cases of quinolone adverse drug reaction in Suzhou city of 2013[J].BEIFANG YAOXUE,2014,0(7):112-113. |
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| Authors: | Guo Xiuxiu |
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| Institution: | Guo Xiuxiu(Anhui Suzhou Institute for Food and Drug Control, Suzhou 234000, China) |
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| Abstract: | Objective Study on the influence factors of adverse drug reactions of quinolones, in order to reduce the occurrence of adverse drug reaction.Methods Collected and analyzed the reports of Quinolones synthetic antibacterial drug adverse reactions in Suzhou city of 2013.Results Levofloxacin induced adverse reaction is most（68.14%）in 748 cases of ADR reports .The adverse drug reactions involving organs or systems mainly reflected in the gastrointestinal system （42.80%）, skin （30.64%）, the central and peripheral nervous system （5.73%）.Conclusion We should strengthen the clinical monitoring of quinolones, to improve security of rational use of drug. |
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| Keywords: | Auinolones Adverse drug reaction（ADR） Synthetic antibacterial drugs |
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